张明曦 副研究员 博士生导师
本科及博士毕业于武汉大学分析化学专业，斯坦福大学研究学者。长期从事纳米生物技术及生物成像方面工作，以第一/通讯作者在Nature Communications、PNAS、Advanced Materials、ACS Nano等国际著名期刊上等上发表研究论文30余篇，主持国家自然科学基金2项，获批发明专利4项。
研究领域
1.功能纳米材料
2.纳米生物技术
3.生物成像
科研项目
1. 国家自然科学基金面上项目：近红外IIb区荧光量子点活体探针用于脑胶质瘤精准成像研究（21974104） 主持
2. 国家自然科学基金青年基金：基于"模块化"设计构建手性响应纳米粒子用于对映体识别（21105078） 主持
3. 第49批中国博士后科学基金面上一等资助：“模块型”手性响应金纳米粒子用于对映体识别研究（20110490121） 主持
教育及工作经历
1.武汉理工大学材料复合新技术国家重点实验室博士后/副研究员（2010.07-至今）
2.斯坦福大学访问学者（2016.07-2017.07）
3.武汉大学化学与分子科学学院分析化学专业硕博连读（2004.09-2010.06）
4.武汉大学化学与分子科学学院化学基地班（2000.09-2004.06）
代表性论文
1.Biao Huang, Tao Tang, Shi-Hui Chen, Hao Li, Zhi-Jun Sun,* Zhi-Lin Zhang,* Mingxi Zhang,* Ran Cui.* Near-infrared-IIb emitting single-atom catalyst for imaging-guided therapy of blood-brain barrier breakdown after traumatic brain injury. Nat. Commun. 2023, 14, 197.
2.Hao Li, Meng Wang, Biao Huang, Su-Wen Zhu, Jun-Jie Zhou, De-Run Chen, Ran Cui,* Mingxi Zhang,* and Zhi-Jun Sun.* Theranostic near-infrared-IIb emitting nanoprobes for promoting immunogenic radiotherapy and abscopal effects against cancer metastasis, Nat. Commun., 2021, 12, 7149.
3.Mingxi Zhang, Jingying Yue, Ran Cui, Zhuoran Ma, Hao Wan, Feifei Wang, Shoujun Zhu, Ying Zhou, Yun Kuang, Yeteng Zhong, Dai-Wen Pang, and Hongjie Dai.* Bright quantum dots emitting at ∼1,600 nm in the NIR-IIb window for deep tissue fluorescence imaging, Proc. Natl. Acad. Sci. USA, 2018, 115, 6590-6595.
4.Feng Liu, Biao Huang, Tao Tang, Fanjie Wang, Ran Cui,* Mingxi Zhang,* Taolei Sun.* Near-infrared-IIb fluorescent nanozymes for imaging-guided treatment of traumatic brain injury. Chem. Eng. J. 2023, 471 144697.
5.Guang-Tao Yu, Meng-Yao Luo, Hao Li, Song Chen, Biao Huang, Zhi-Jun Sun,* Ran Cui,* and Mingxi Zhang.* Molecular Targeting Nanoprobes with Non-Overlap Emission in the Second Near-Infrared Window for in Vivo Two-Color Colocalization of Immune Cells, ACS Nano, 2019, 13, 12830-12839.
6.Lu-Yao Huang, Shoujun Zhu, Ran Cui,* and Mingxi Zhang.* Noninvasive In Vivo Imaging in the Second Near-Infrared Window by Inorganic Nanoparticle-Based Fluorescent Probes, Anal. Chem., 2020, 92: 535-542.
7.Tian, Rui; Ma, Huilong; Zhu, Shoujun*; Lau, Joseph; Ma, Rui; Liu, Yijing; Lin, Lisen; Chandra, Swati; Wang, Sheng; Zhu, Xingfu; Deng, Hongzhang; Niu, Gang; Zhang, Mingxi*; Antaris, Alexander L.; Hettie, Kenneth S.; Yang, Bai; Liang, Yongye*; Chen, Xiaoyuan*; Multiplexed NIR-II Probes for Lymph Node-Invaded Cancer Detection and Imaging-Guided Surgery, Adv. Mater., 2020, 32: 1907365.
8.Xiulei Shi, Song Chen, Meng-Yao Luo, Biao Huang, Guozhen Zhang, Ran Cui, and Mingxi Zhang.* Zn-doping enhances the photoluminescence and stability of PbS quantum dots for in vivo high-resolution imaging in the NIR-II window, Nano Res., 2020, 13, 2239-45.
9.Zhe Feng, Tao Tang, Tianxiang Wu, Xiaoming Yu, Yuhuang Zhang, Meng Wang, Junyan Zheng, Yanyun Ying, Siyi Chen, Jing Zhou, Xiaoxiao Fan, Dan Zhang, Shengliang Li, Mingxi Zhang,* and Jun Qian.* Perfecting and extending the near-infrared imaging window, Light Sci. Appl., 2021, 10, 197.
10.Meng Wang, Hao Li, Biao Huang, Song Chen, Ran Cui, Zhi-Jun Sun,* Mingxi Zhang,* and Taolei Sun.* An Ultra-Stable, Oxygen-Supply Nanoprobe Emitting in Near-Infrared-II Window to Guide and Enhance Radiotherapy by Promoting Anti-Tumor Immunity, Adv. Healthcare Mater., 2021, 10, 2100090.
联系方式
通讯地址：武汉市洪山区珞狮路122号武汉理工大学马房山校区材料复合新技术国家重点实验室
邮箱地址：mxzhang@whut.edu.cn
